Frequently Asked Questions
- What is VIMOVO?
- What is the most important information I should know about VIMOVO?
- How can I get VIMOVO?
- Who should not take VIMOVO?
- What should I tell my health care provider before starting VIMOVO?
- Can I take VIMOVO if I am taking other medicines?
- Where can I get more information about VIMOVO?
- What is an NSAID?
- What is Esomeprazole Magnesium?
- How should I take VIMOVO?
- What do I do if I think I have taken too much VIMOVO?
- What if I forget to take a dose of VIMOVO?
- How should I store my VIMOVO?
What is VIMOVO?
VIMOVO is a prescription 2-in-1 combination tablet that contains 2 medicines, Naproxen and Esomeprazole magnesium
- Naproxen is a nonsteroidal anti-inflammatory drug (NSAID)
- Esomeprazole magnesium is a Proton Pump Inhibitor, a medicine that may help reduce stomach acid
VIMOVO is used to:
- Relieve the signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis in adults and juvenile idiopathic arthritis (JIA) in adolescent patients
- Decrease the risk of developing ulcers in the stomach in patients who are taking naproxen.
- It is not known if VIMOVO is safe and effective in children less than 12 years of age or who weigh less than 84 pounds (38 kg).
What is the most important information I should know about VIMOVO?
You should take VIMOVO exactly as prescribed, at the lowest dose possible and for the shortest time needed. VIMOVO may help your acid-related symptoms, but you could still have serious stomach problems.
VIMOVO contains naproxen (an NSAID) and esomeprazole magnesium. NSAID-containing medicines, such as VIMOVO, increase the chance of a heart attack or stroke that can lead to death. This risk may occur early in treatment. This chance increases:
- With increasing doses of medicine containing NSAIDs
- With longer use of medicines containing NSAIDs
VIMOVO should never be used right before or after a heart surgery called a coronary artery bypass graft (CABG). You may have an increased risk of another heart attack if you take NSAIDs after a recent heart attack.
NSAID-containing medicines, such as VIMOVO, can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding:
- Can occur anytime during use
- Can happen without warning symptoms
- May cause death
The chance of a person getting an ulcer or bleeding with NSAIDs increases with:
- Past history of stomach ulcers, or stomach or intestinal bleeding with use of NSAIDs
- Taking medicines called “corticosteroids”, “anticoagulants”, “SSRIs”, or “SNRIs”
- Longer use of NSAIDs
- Increasing doses of NSAIDs
- Drinking alcohol
- Older age
- Advanced liver disease
- Bleeding problems
- Having poor health
Talk to your healthcare provider or pharmacist before using other medicines that contain NSAIDs, including low-dose aspirin, during treatment with VIMOVO.
How can I get VIMOVO?
VIMOVO is available by prescription only. Ask your health care provider if VIMOVO may be right for you.
Who should not take VIMOVO?
You should not take VIMOVO:
- If you had an asthma attack, hives or other allergic reaction after taking aspirin or other NSAID medicines
- Right before or after a heart surgery called coronary artery bypass graft surgery
- If you are taking a medicine that contains rilpivirine (Edurant, Complera, Odefsey) used to treat HIV-1 (Human Immunodeficiency Virus)
- If you know you are allergic to naproxen, esomeprazole magnesium, omeprazole, any other PPI medicine or any of the ingredients in VIMOVO
- If you are in the late stages of pregnancy (after 29 weeks of pregnancy)
What should I tell my health care provider before starting VIMOVO?
Before you take VIMOVO, you should tell your health care provider if you:
- Have asthma
- Have high blood pressure (hypertension)
- Have heart problems
- Have low magnesium levels in your blood
- Have ulcerative colitis or Crohn’s disease (inflammatory bowel disease or IBD)
- Have a history of stomach ulcers
- Take or plan to take low-dose aspirin
- Have liver or kidney problems
- Have any other medical conditions
- Are pregnant or plan to become pregnant. VIMOVO should not be used by pregnant women late in their pregnancy. See Medication Guide for more information
- Are breastfeeding or plan to breastfeed. VIMOVO can pass into your milk and may harm your baby. You should not breastfeed while taking VIMOVO. Talk to your health care provider about the best way to feed your baby if you take VIMOVO
Can I take VIMOVO if I am taking other medicines?
You should tell your health care provider about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal supplements. Since VIMOVO contains naproxen, talk to your health care provider before taking any other NSAID-containing products. NSAIDs may be present in over-the-counter medications for treatment of colds, fever or insomnia; refer to the label of over-the-counter medications you are taking or ask your pharmacist.
Using VIMOVO with other medicines can cause serious side effects. VIMOVO may affect the way other medicines work, and other medicines may affect how VIMOVO works. Especially tell your doctor if you take:
- Aspirin, Warfarin (Coumadin, Jantovin), Rifampin (Rifater, Rifamate, Rimactane, Rifadin), Digoxin (Lanoxin) and Clopidogrel (Plavix)
- Medications for high blood pressure or heart problems
- Methotrexate (Otrexup, Rasuvo, Trexall, Xatmep)
- Steroid Hormones (corticosteroids)
- St. John’s Wort
Where can I get more information about VIMOVO?
Ask your health care provider about VIMOVO; only your health care provider can offer information that is specific to your own health history.
What is an NSAID?
Nonsteroidal anti-inflammatory drugs are used to treat pain and redness, swelling and heat (inflammation) from medical conditions, including different types of arthritis (e.g., osteoarthritis and rheumatoid arthritis)
What is Esomeprazole Magnesium?
Esomeprazole magnesium is a Proton Pump Inhibitor (PPI), a medicine that may help reduce stomach acid
How should I take VIMOVO?
- Take VIMOVO exactly as prescribed by your health care provider
- Take 1 VIMOVO tablet 2 times each day
- Take VIMOVO at least 30 minutes before a meal
- Swallow VIMOVO tablets whole with liquid. Do not split, chew, crush, or dissolve VIMOVO
- You can use antacids while taking VIMOVO
What do I do if I think I have taken too much VIMOVO?
If you take too much VIMOVO, call your healthcare provider or your poison control center at 1-800-222-1222 right away or go to the nearest emergency room.
What if I forget to take a dose of VIMOVO?
If you forget to take a dose of VIMOVO, take it as soon as you remember. If it is almost time for your next dose, do not take the missed dose. Take the next dose on time. Do not take 2 doses at 1 time to make up for a missed dose.
How should I store my VIMOVO?
- Store VIMOVO at room temperature between 68°F to 77°F (20°C to 25°C)
- Store VIMOVO in the original container and keep the bottle tightly closed